Polyphenols

Responsible: Josep Valls–Fonayet

This activity specializes in targeted and untargeted analyses of compounds of interest in plants, particularly grapevine and grapevine-derived products.

The platform performs compositional analyses of grapevine and wine matrices, with a particular focus on polyphenols, aroma compounds, sugars and amino acids.

Analytical Equipement

  • UHPLC-UV-Q-Orbitrap
  • UHPLC-DAD-Q-TOF
  • UHPLC-UV-QQQ
  • 500 MHz NMR
  • 250 mL CPC

Applications

  • Wine authenticity and traceability
  • Characterization of plant matrices
  • Investigation of polyphenol metabolism
  • Structural elucidation of specialized metabolites
  • Annotation of stilbenes and other compounds in plant extracts
  • Investigation of the impact of polyphenols on human health
  • Correlation of the phenolic composition of extracts with grapevine protection
  • Valorization of co-products

Key publications

  • Guillaume Leleu, Rémi Butell, Patricia Homobono de Moura, Josep Valls-Fonayet, Grégory Da Costa, Tristan Richard (2026). Wine authenticity controls: Analytical methods, data integration and emerging perspectives. Food Analytical Methods. https://doi.org/10.1007/s12161-026-03027-6 
  • Julie Miranda, Marguerite Dols-Lafargue, Caroline Rouger (2026). Linking red wine chemical composition with vulnerability to Brettanomycesbruxellensis development through untargeted metabolomics. Food Chemistry. https://doi.org/10.1016/j.foodchem.2026.150179 
  • Charles Tardif, Caroline Rouger, Julie Miranda, Omar S. Ahmed, Florence Richard-Forget, Vessela Atanasova, Pierre Waffo-Teguo (2024). Targeting of antifungal metabolites from grapevine byproducts by UPLC-HRMS/MS approaches using bioactivity-based molecular networking. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.3c09531 
  • Karen Gaudin, Josep Valls-Fonayet, Rémy Cordazzo, WiktoriaSerafin, Emma Lafon, Alexandra Gaubert, Tristan Richard, Stéphanie Cluzet (2024). Separation of polyphenols by HILIC methods with diode array detection, charged aerosol detection and mass spectrometry: Application to grapevine extracts rich in stilbenoids. Journal of Chromatography A. https://doi.org/10.1016/j.chroma.2024.465422 GrégoireLoupit, Sylvain Prigent, Céline Franc, Gilles De Revel, Tristan Richard, Sarah Jane Cookson, Josep Valls Fonayet (2020). Polyphenol profiles of just pruned grapevine canes from wild Vitisaccessions and Vitis vinifera cultivars. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.9b08099